- New block polymer phases discovered by CEMS team featured in Science
- Research published in Biomicrofluidics could advance genome mapping technology
- Collaborative research on block polymer simulations featured in Macromolecules
- Researchers at UMN and BioNano Genomics improving genome mapping
- Muralidhar wins grand prize in MSI Research Exhibition
- Dorfman research highlighted in LC/GC newsletter
The research currently underway in the group centers around questions in polymer physics and microfluidic/nanofluidic technologies. On the polymer side, we are particularly interested in understanding the dynamics of DNA in confined systems, which allows us to simultaneously investigate the basic physical properties of semiflexible polymers while advancing genomics applications. In this area, we use a combination of experimental tools (fluorescence microscopy and nanofabrication), simulations (Brownian dynamics and Monte Carlo) and theory. There is a growing interest in the group on the thermodynamics of block polymers, largely in collaboration with Frank Bates, taking advantage of self-consistent field theory to study the formation of complex phases. On the microfluidics side, we have been working closely with Dan Frisbie on the development of new biosensors based on printed electronics and DNA aptamers. We are also using microchemostats developed in the group to study gene expression and the dynamics of bacterial DNA as part of a larger HFSP-funded collaboration.
- Mid-Career Award of the AES Electrophoresis Society, 2014
- AIChE Colburn Award, 2012
- Guillermo E. Borja Award, 2012
- Camille Dreyfus Teacher-Scholar Award, 2010
- DARPA Young Faculty Award, 2009
- Packard Fellowship in Science and Engineering, 2007
- NSF CAREER Award, 2007
- Camille and Henry Dreyfus Foundation New Faculty Award, 2006
- Human Frontier Science Program Career Development Award, 2006
- Scott P. White, C. Daniel Frisbie and Kevin D. Dorfman, Detection and sourcing of gluten in grain with multiple floating-gate transistor biosensors. ACS Sensors 3, 395-402 (2018).
- Kyungtae Kim, Akash Arora, Ronald M. Lewis III, Meijiao Liu, Weihua Li, An-Chang Shi, Kevin D. Dorfman and Frank S. Bates, Origins of low symmetry phases in asymmetric diblock copolymer melts. Proceedings of the National Academy of Sciences USA 115, 847-854 (2018).
- Hui-Min Chuang, Jeffrey G. Reifenberger, Han Cao and Kevin D. Dorfman, Sequence-dependent persistence length of long DNA. Physical Review Letteres 119, 227802 (2017)
- Erik Werner, Guo-Kang Cheong, Damini Gupta, Kevin D. Dorfman and Bernhard Mehlig, One-parameter scaling theory for DNA extension in a nanochannel. Physical Review Letters 119, 268102 (2017).
- Kyungtae Kim, Morgan W. Schulze, Akash Arora, Ronald M. Lewis III, Marc A. Hillmyer, Kevin D. Dorfman and Frank S. Bates. Thermal processing of diblock copolymer melts mimics metallurgy. Science 356, 520-523 (2017).
- Akash Arora, Jian Qin, David C. Morse, Kris T. Delaney, Glenn H. Fredrickson, Frank S. Bates, and Kevin D. Dorfman, Broadly accessible self-consistent field theory for block polymer materials discovery. Macromolecules 49, 4675-4690 (2016).
- Douglas R. Tree, Yanwei Wang and Kevin D. Dorfman, Extension of DNA in a nanochannel as a rod-to-coil transition. Physical Review Letters 110, 208103 (2013).
- Liang Dai, Douglas R. Tree, Johan R. C. van der Maarel, Kevin D. Dorfman and Patrick S. Doyle, Revisiting blob theory for DNA diffusivity in slitlike confinement. Physical Review Letters 110, 168105 (2013).
- Kevin D. Dorfman, Scott B. King, Daniel W. Olson, Joel D. P. Thomas and Douglas R. Tree, Beyond gel electrophoresis: Microfluidic separations, fluorescence burst analysis, and DNA stretching. Chemical Reviews 113, 2584-2667 (2013).
- Kevin D. Dorfman and Prodromos Daoutidis, Numerical Methods with Chemical Engineering Applications, Cambridge University Press (2017)